Setd3 (BC019973) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR209250 representing BC019973 Red=Cloning site Green=Tags(s) MGKKSRVKTQKSGTGATATVSPKEILNLTSELLQKCSSPAPSPGKEWEEYTQIRALVEKIRKKQKGLSVT FDGKREDYFPDLMKWASENGASVEGFEMVNFKEEGFGLRATRDIKAEELFLWVPRKLLMTVESAKNSVLG PLYSQDRILQAMGNIALAFHLLCERASPNSFWQPYIQTLPSEYDTPLYFEEEEVRCLQSTQAIHDVFSQY KNTARQYAYFYKVIQTHPHANKLPLKESFTYEDYRWAVSSVMTRQNQIPTEDGSRVTLALIPLWDMCNHT NGLITTGYNLEDDRCECVALQDFQAGDQIYIFYGTRSNAEFVIHSGFFFDNNSHDRVKIKLGVSKSDRLY AMKAEVLARAGIPTSSVFALHSTEPPISAQLLAFLRVFCMTEEELKEHLLGDSAIDRIFTLGNAEFPVSW DNEVKLWTFLEDRASLLLKTYKTTIEEDKIVLKNPDLSVRATMAIKLRLGEKEILEKAVKSAAVNREYYR KHMEERAPLPRYEESDLGLLEGGVGDSRLPLVLRKLEEEAGVQESLSLTETVSKVKAAENGLVNGENLIP NGTRSENESLSPEESENVTGEESSGSMAKVKERL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	90.8 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
Locus ID	52690
UniProt ID	Q91WC0
Refseq Size	2477
Cytogenetics	12 59.23 cM
Refseq ORF	1782
Synonyms	2610102I01Rik; 2610305M23Rik; 6030490B17Rik; D12Ertd771e
Summary	Protein-histidine N-methyltransferase that specifically mediates methylation of actin at 'His-73' (PubMed:30626964). Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery (PubMed:30626964). Does not have protein-lysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin (PubMed:30626964).[UniProtKB/Swiss-Prot Function]

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