Kif2c (NM_134471) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR210280 protein sequence Red=Cloning site Green=Tags(s) MESLHARLFPGLSINIQRSNGLIHPANISTVNVEKSCVSVEWIEGGTTKGKEIDIDDVAAINPELLQLLP LRPKDSLPLQENVTVPKQKRKSVNSKIPALKEGLRSRSTRMSTVSEVRIPAQENEMEVELPVPTNSRKQF AIPSHPRASCSTVTELPLLMVSEEAEEQAHSTRSTSSANPGNSVRRKSCIVKEMEKMKNKREEKRAQNSE LRIKRAQEYDSSFPNWEFARMIKEFRVTMECSPLTVTDPIEEHRICVCVRKRPLNKQELAKKEIDVISVP SKCLLLVHEPKLKVDLTKYLENQAFCFDFAFDETASNEVVYRFTARPLVQTIFEGGKATCFAYGQTGSGK THTMGGDLSGKSQNASKGIYAMASRDVFLLKNQPRYRNLNLEVYVTFFEIYNGKVFDLLNKKAKLRVLED SRQQVQVVGLQEYLVTCADDVIKMINMGSACRTSGQTFANSNSSRSHACFQILLRTKGRLHGKFSLVDLA GNERGADTSSADRQTRMEGAEINKSLLALKECIRALGQNKAHTPFRESKLTQVLRDSFIGENSRTCMIAM ISPGISSCEYTLNTLRYADRVKELSPHSGPSGEQPVQMETEVMEASSNGTSLTGNEEEELSSQMSSFNEA MTQIRELEERALEELREIIQQGPNWLELSEMTDQPDYDLETFVNKAESALTQQAKQAKHFSALREVIKAL RLAMQLEEQASKQINSKKRHQ TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	81.1 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_608301
Locus ID	73804
UniProt ID	Q922S8
Refseq Size	2840
Cytogenetics	4 53.42 cM
Refseq ORF	2163
Synonyms	4930402F02Rik; ESTM5; Knsl6; MCAK; X83316
Summary	In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells (PubMed:14980225). Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis. Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome-microtubule attachment (By similarity).[UniProtKB/Swiss-Prot Function]

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