Ccdc120 (NM_207202) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR212419 protein sequence Red=Cloning site Green=Tags(s) MEVKGQLISSPTFTAPAALFGEAAPLVKSDRLRGLLDRQRALQEALSVKLQELRKVCLQEAELTGQLPPE CPLEPGERPQLVRRRPPAARAYPPPHPNPAHHSLCPAEELALEALEREVSVQQQIAAAARRLALAPDLNG EQRRRRRQVQVDALRRLHELEEQLRDFRARLGLPVLQPLPLSAGALVNAQGVCLGTRLAQLSQEDVVLHS ESSSLSESGASHDNEEPHSCFPLTERPSPPKAWDQFRAVSGGSPERRAPWKPPPSDIYGDLKSRRNSVAS PTSPTRSLPRSASSFEGRSVPATPVLTRGSGPRLCKPEGLHSRQWSGSQDSQMGFPRPDPASDRASLFAA RTRRSNSSEALLVDRAAAGGAGSPPAPLAPPAAGPPVCKSSEVLYERPQPVPSFSSRTTGPPDPPRAARP SSAAPASRGAPRLPTVCGDFLLDYPLDRGLPRGSGGAGWGELLPAPEVPGPLSRRDGLLAMLPGPPPIYA ADGSSPLLRSKDPNTRAIRSKPSGLPPEAVEGLEVHPNPLLWMPPPTRIPPAGERGGHKNLALEGLRDWY IRNSGLAVGPQRRPMLPHVGPTHTPFLHARCYEVGQSLYGPPSQAPLPHSRSFTAPPVSGRYGGAFTDG TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	67.4 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_997085
Locus ID	54648
UniProt ID	A2AEV7
Refseq Size	3641
Cytogenetics	X 3.48 cM
Refseq ORF	1887
Synonyms	AA030924; DXImx50e; Jm11; Sfc25
Summary	Centriolar protein required for centriole subdistal appendage assembly and microtubule anchoring in interphase cells (PubMed:28422092). Together with CCDC68, cooperate with subdistal appendage components ODF2, NIN and CEP170 for hierarchical subdistal appendage assembly (PubMed:28422092). Recruits NIN and CEP170 to centrosomes (PubMed:28422092). Also required for neurite growth (By similarity). Localizes CYTH2 to vesicles to allow its transport along neurites, and subsequent ARF6 activation and neurite growth (By similarity).[UniProtKB/Swiss-Prot Function]

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