Spindoc (NM_001167831) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR214873 representing NM_001167831 Red=Cloning site Green=Tags(s) MALKAKGAAALDCFEVTLKCEEGDDDDEAVVVAVIPRPEPMLRVTQQEKTPPPRPNLLEAGVEGCEELKQ QVSWEQEFLVGNSPGGSGRALCMVCGAEIRSPSADTARAHILEQHPHTLDLSPSEKSNILEAWSEGVALL QDIQADQPSLPSLESGQDGQPDPISNPDPVRMPAEIVVLLDSEDNPSLPKRLRPRGLRPLELPVTPVIEQ GNKKPRGQRWKESPENEPARKKRSRHMTKILDPDPDPPSPESPTETFAAPAEVRHFTDGSFPPGFVLQLF SHTQLRTTDCKDSSKDSRAAEGLPQPQNPSSGEPC TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	34.8 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_001161303
Locus ID	68229
UniProt ID	Q05AH6
Refseq Size	1594
Cytogenetics	19 A
Refseq ORF	945
Synonyms	1700105P06Rik; AI846148; SPIN-DOC
Summary	Negatively regulates the transcriptional activator activity of SPIN1 via inhibition of its histone methyl-binding ability. Represses the expression of a number of SPIN1-regulated genes and the SPIN1-mediated activation of the Wnt signaling pathway (PubMed:29061846). Can also inhibit the histone methyl-binding abilities of SPIN2A, SPIN2B, SPIN3 and SPIN4 (By similarity).[UniProtKB/Swiss-Prot Function]

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