ICOS (NM_012092) Human Recombinant Protein

Specifications

Product Data
Species	Human
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) A DNA sequence from TrueORF clone, RC207031, encoding the region (Glu21 – Lys140) of human ICOS
Tag	C-Fc/His
Predicted MW	39 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	PBS, pH 7.4, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_036224
Locus ID	29851
UniProt ID	Q9Y6W8
Refseq Size	2652
Cytogenetics	2q33.2
Refseq ORF	597
Synonyms	AILIM; CD278; CVID1
Summary	The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. [provided by RefSeq, Jul 2008]
Protein Families	Secreted Protein, Transmembrane
Protein Pathways	Cell adhesion molecules (CAMs), Primary immunodeficiency, T cell receptor signaling pathway

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