RAGE (AGER) (NM_001136) Human Recombinant Protein
CAT#: TP720357XL
Recombinant protein of human advanced glycosylation end product-specific receptor (AGER), transcript variant 1
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CNY 25,350.00
货期*
2周
规格
经常一起买 (1)
Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
Ala23-Ala344
|
Tag | C-His |
Predicted MW | 35.2 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Provided lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl |
Storage | Store at -80°C. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Bioactivity | Binding assay (PMID: 29420566) |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Reference Data | |
RefSeq | NP_001127 |
Locus ID | 177 |
UniProt ID | Q15109, A0A1U9X785, B4DNX3 |
Cytogenetics | 6p21.32 |
Synonyms | RAGE; SCARJ1; sRAGE |
Summary | The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847). [provided by RefSeq, May 2011] |
Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
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