PAI1 (SERPINE1) (NM_000602) Human Recombinant Protein
CAT#: TP720683
Purified recombinant protein of Human serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 (SERPINE1), transcript variant 1
View other "PAI1" proteins (7)
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CNY 1800.00
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Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
Val24-Pro402
|
Tag | C-His |
Predicted MW | 43.82 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 um filtered solution of 20mM HAc-NaAc, 150mM NaCl, pH 4.0. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Reference Data | |
RefSeq | NP_000593 |
Locus ID | 5054 |
UniProt ID | P05121 |
Refseq Size | 3207 |
Cytogenetics | 7q22.1 |
Refseq ORF | 1206 |
Synonyms | PAI; PAI-1; PAI1; PLANH1 |
Summary | This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. The protein also functions as a component of innate antiviral immunity. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. [provided by RefSeq, Aug 2020] |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Complement and coagulation cascades, p53 signaling pathway |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC424612 | SERPINE1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LC431339 | SERPINE1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LY424612 | Transient overexpression lysate of serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 (SERPINE1), transcript variant 1 |
CNY 3080.00 |
|
LY431339 | Transient overexpression lysate of serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 (SERPINE1), transcript variant 2 |
CNY 3080.00 |
|
PH302085 | SERPINE1 MS Standard C13 and N15-labeled recombinant protein (NP_000593) |
CNY 19520.00 |
|
TP302085 | Recombinant protein of human serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 (SERPINE1), 20 µg |
CNY 2900.00 |
|
TP701235 | Purified recombinant protein of Human serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 (SERPINE1), full length, with C-terminal His tag, secretory expressed in HEK293 cells, 50ug |
CNY 2900.00 |