LI Cadherin (CDH17) Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	Human 293
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Gln23-Met787
Tag	C-6His
Buffer	Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH7.4
Note	Recombinant Human Cadherin-17 is produced by our Mammalian expression system and the target gene encoding Gln23-Met787 is expressed with a 6His tag at the C-terminus.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Locus ID	1015
UniProt ID	Q12864
Synonyms	Cadherin-17; Intestinal Peptide-Associated Transporter HPT-1; Liver-Intestine Cadherin; LI-Cadherin; CDH17
Summary	Cadherin-17 is a single-pass type I membrane protein that belongs to the cadherin superfamily. Cadherin17 consists of one extracellular region containing seven cadherin domains and one transmembrane region but it lacks the conserved cytoplasmic domain. Cadherin-17 is expressed in the gastrointestinal tract and pancreatic duct. Cadherins are calcium dependent cell adhesion proteins and preferentially interact with each other in a homophilic manner in connecting cells. Cadherin-17 may have a role in the morphological organization of liver and intestine and involved in intestinal peptide transport.
Protein Families	Transmembrane

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