Gasdermin D (GSDMD) (NM_024736) Human Recombinant Protein
CAT#: TP761411
Purified recombinant protein of Human gasdermin D (GSDMD), transcript variant 1, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug
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CNY 2040.00
货期*
现货
规格
| Cited in 1 publication. |
推荐一起购买 (1)
Specifications
| Product Data | |
| Species | Human |
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length GSDMD
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| Tag | N-GST and C-His |
| Predicted MW | 80.6 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_079012 |
| Locus ID | 79792 |
| UniProt ID | P57764 |
| Refseq Size | 1772 |
| Cytogenetics | 8q24.3 |
| Refseq ORF | 1452 |
| Synonyms | DF5L; DFNA5L; FKSG10; GSDMDC1 |
| Summary | Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009] |
Citations (1)
| The use of this Proteins has been cited in the following citations: |
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The colonic pathogen Entamoeba histolytica activates caspase-4/1 that cleaves the pore-forming protein gasdermin D to regulate IL-1β secretion
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PLoS Pathogens
,PubMed ID 35303042
[GSDMD]
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