IRE1 (ERN2) (NM_033266) Human Recombinant Protein

Specifications

Product Data
Species	Human
Expression Host	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) A DNA sequence encoding the region (Asp320-Asp617) of ERN2
Tag	N-His
Predicted MW	32.5 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	>80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	50 mM Tris-HCl, pH 8.0, 8 M urea
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_150296
Locus ID	10595
UniProt ID	Q76MJ5, A5YM46, A5YM65
Refseq Size	3549
Cytogenetics	16p12.2
Refseq ORF	2922
Synonyms	hIRE2p; IRE1-BETA; IRE1b; IRE2p
Summary	Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins.[UniProtKB/Swiss-Prot Function]
Protein Families	Druggable Genome, Protein Kinase

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