Serine Palmitoyltransferase (SPTLC2) (NM_004863) Human Recombinant Protein

Specifications

Product Data
Species	Human
Expression Host	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) A DNA sequence encoding the region full length of SPTLC2
Tag	N-GST and C-HIS
Predicted MW	62.9 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	50mM Tris, pH8.0, 8M Urea
Storage	Store at -80°C after receiving vials.
Stability	Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_004854
Locus ID	9517
UniProt ID	O15270, A0A024R6H1
Refseq Size	8164
Cytogenetics	14q24.3
Refseq ORF	1686
Synonyms	hLCB2a; HSN1C; LCB2; LCB2A; NSAN1C; SPT2
Summary	This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011]
Protein Pathways	Metabolic pathways, Sphingolipid metabolism

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