Sec14l2 Mouse shRNA Plasmid (Locus ID 67815)
CAT#: TL510781
Sec14l2 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
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CNY 7740.00
货期*
2周
规格
Cited in 1 publication. |
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Specifications
Product Data | |
Product Name | Sec14l2 Mouse shRNA Plasmid (Locus ID 67815) |
Locus ID | 67815 |
UniProt ID | Q99J08 |
Synonyms | 1300013M05Rik; Spf; TAP |
Vector | pGFP-C-shLenti |
Format | Lentiviral plasmids |
Kit Components | Sec14l2 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 67815). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
RefSeq | BC005759, NM_144520, NM_144520.1, NM_144520.2 |
Summary | Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell (By similarity).[UniProtKB/Swiss-Prot Function] |
shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
Performance Guaranteed | OriGene guarantees that the sequences in the shRNA expression cassettes are verified to correspond to the target gene with 100% identity. One of the four constructs at minimum are guaranteed to produce 70% or more gene expression knock-down provided a minimum transfection efficiency of 80% is achieved. Western Blot data is recommended over qPCR to evaluate the silencing effect of the shRNA constructs 72 hrs post transfection. To properly assess knockdown, the gene expression level from the included scramble control vector must be used in comparison with the target-specific shRNA transfected samples. For non-conforming shRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the shRNA kit. To arrange for a free replacement with newly designed constructs, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled shRNA control (Western Blot data preferred). |
Citations (1)
The use of this RNAi has been cited in the following citations: |
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SEC14L2 enables pan-genotype HCV replication in cell culture
,null,
Nature
,PubMed ID 26266980
[Sec14l2]
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