CCN2 Human siRNA Oligo Duplex (Locus ID 1490)
CAT#: SR301057
CTGF (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
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CNY 3848.00
货期*
5周
规格
Cited in 2 publications. |
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Specifications
Product Data | |
Purity | HPLC purified |
Quality Control | Tested by ESI-MS |
Sequences | Available with shipment |
Stability | One year from date of shipment when stored at -20°C. |
# of transfections | Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM). |
Note | Single siRNA duplex (10nmol) can be ordered. |
Reference Data | |
RefSeq | NM_001901 |
Synonyms | CTGF; HCS24; IGFBP8; NOV2 |
Components | CTGF (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 1490)Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmolIncluded - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml |
Summary | The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009] |
Performance Guranteed | OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required). |
Citations (2)
The use of this RNAi has been cited in the following citations: |
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Angiotensin II induces connective tissue growth factor expression in human hepatic stellate cells by a transforming growth factor β-independent mechanism
,Li, A;Zhang, J;Zhang, X;Wang, J;Wang, S;Xiao, X;Wang, R;Li, P;Wang, Y;,
Sci Rep
,PubMed ID 28798388
[CCN2]
|
KCTD11 inhibits growth and metastasis of hepatocellular carcinoma through activating Hippo signaling
,Tong, R;Yang, B;Xiao, H;Peng, C;Hu, W;Weng, X;Cheng, S;Du, C;Lv, Z;Ding, C;Zhou, L;Xie, H;Wu, J;Zheng, S;,
Oncotarget
,PubMed ID 28465479
[CCN2]
|
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