CD82 Mouse Monoclonal Antibody [Clone ID: C33]

Specifications

Product Data
Clone Name	C33
Applications	FC, FN, IF, IHC, IP, WB
Recommend Dilution	Flow Cytometry. Immunoprecipitation Western blot. Immunohistochemistry on Paraffin Sections. Immunocytochemistry. Functional Application: In Human MOLT-4 T-cell line the antibody C33 inhibits syncytium formation induced by coculture with Human T-cell leukemia virus type 1 (HTLV-1)-positive Human T-cell lines.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	C91/PL (Human HTLV-1+ T cell line)
Specificity	The antibody reacts with CD82, a widely expressed cell surface protein of the tetraspanin family. CD82 is also found in endosome/lysosome compartments.
Formulation	Phosphate buffered saline (PBS), approx. pH 7.4 State: Aff - Purified State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE) Preservative: 15 mM Sodium Azide
Concentration	lot specific
Purification	Protein-A Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	CD82 molecule
Database Link	Entrez Gene 3732 Human UniProt ID P27701
Background	CD82 (KAI1), a member of the tetraspanin family, forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules. These complexes influence adhesion, morphology, activation, proliferation and differentiation of B, T and other cells. CD82 regulates cytoskeleton rearrangement and may participate in the turnover of the tetraspanin complex members. Besides in the plasma membrane, CD82 is localized also in endosome/lysosome compartments. Tumour-suppressive roles of CD82 have been demonstrated.
Synonyms	KAI1, SAR2, ST6, TSPAN27, C33 antigen, IA4, Kangai-1, Tetraspanin-27
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.