CD82 Mouse Monoclonal Antibody [Clone ID: C33]

Specifications

Product Data
Clone Name	C33
Applications	FC
Recommend Dilution	Flow Cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	C91/PL (human HTLV-1+ T cell line)
Specificity	This antibody reacts with CD82, a widely expressed cell surface protein of the tetraspanin family. CD82 is also found in endosome/lysosome compartments.
Formulation	Phosphate buffered saline (PBS) Label: PE State: Liquid Ig fraction Preservative: 15 mM sodium azide
Purification	Size-exclusion chromatography
Conjugation	PE
Storage Condition	Store undiluted at 2-8°C. Do Not Freeze! This products is photosensitive and should be protected from light.
Gene Name	CD82 molecule
Database Link	Entrez Gene 3732 Human UniProt ID P27701
Background	CD82 (KAI1), a member of the tetraspanin family, forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules. These complexes influence adhesion, morphology, activation, proliferation and differentiation of B, T and other cells. CD82 regulates cytoskeleton rearrangement and may participate in the turnover of the tetraspanin complex members. Besides in the plasma membrane, CD82 is localized also in endosome/lysosome compartments. Tumour-suppressive roles of CD82 have been demonstrated.
Synonyms	KAI1, SAR2, ST6, TSPAN27, C33 antigen, IA4, Kangai-1, Tetraspanin-27
Reference Data

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