Hsp105 (HSPH1) Rabbit Polyclonal Antibody
CAT#: TA321775S
Anti-HSPH1 Rabbit Polyclonal Antibody
Size: 100 ul
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Specifications
| Product Data | |
| Applications | WB |
| Recommend Dilution | WB: 500-2000 WB positive control: PC3 cells, human colon cancer and liver cancer tissue |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to C terminal 300 amino acids of human heat shock 105kDa/110kDa protein 1 |
| Isotype | IgG |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 97 kDa |
| Gene Name | heat shock protein family H (Hsp110) member 1 |
| Database Link | |
| Background | Heat shock protein 105 kDa?is a?protein?that in humans is encoded by the?HSPH1?gene. Prevents the aggregation of denatured proteins in cells under severe stress; on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities. Highly expressed in testis. Present at lower levels in most brain regions; except cerebellum. Overexpressed in cancer cells. Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity. |
| Synonyms | HSP105; HSP105A; HSP105B; NY-CO-25 |
| Reference Data | |
| Protein Families | Stem cell - Pluripotency |
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