NME6 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 200-1000 WB positive control: Mouse spleen and intestinum crassum tissue
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Full length fusion protein
Isotype	IgG
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	21 kDa
Gene Name	NME/NM23 nucleoside diphosphate kinase 6
Database Link	NP_005784 Entrez Gene 54369 MouseEntrez Gene 58964 RatEntrez Gene 10201 Human UniProt ID O75414
Background	Nucleoside diphosphate (NDP) kinases (EC 2.7.4.6); such as NME6; are ubiquitous enzymes that catalyze transfer of gamma-phosphates; via a phosphohistidine intermediate; between nucleoside and dioxynucleoside tri- and diphosphates. Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism; using a phosphorylated active-site intermediate. Inhibitor of p53-induced apoptosis.
Synonyms	IPIA-ALPHA; NDK 6; NM23-H6
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Metabolic pathways, Purine metabolism, Pyrimidine metabolism

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