Profilin 1 (PFN1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 200-1000 WB positive control: Jurkat and 231 cells
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 2-140 amino acids of human profilin 1
Isotype	IgG
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	15 kDa
Gene Name	profilin 1
Database Link	NP_005013 Entrez Gene 18643 MouseEntrez Gene 64303 RatEntrez Gene 5216 Human UniProt ID P07737
Background	This gene encodes a member of the profilin family of small actin-binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome; and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1.?
Synonyms	ALS18
Reference Data
Protein Families	Druggable Genome, Stem cell - Pluripotency
Protein Pathways	Regulation of actin cytoskeleton

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