Caldesmon (CALD1) Rabbit Polyclonal Antibody
CAT＃: TA322766S
Anti-CALD1 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1280.00
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CNY 300.00
CNY 1430.00
CNY 2900.00
CNY 6650.00
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB: 1000-5000 WB positive control: 293T cells IHC: 50-150 Positive control: Human testis Predicted cell location: Cytoplasm |
| Reactivity | Human, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to a region derived from 26-207 amino acids of human caldesmon 1 |
| Isotype | IgG |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 63 kDa |
| Gene Name | caldesmon 1 |
| Database Link | |
| Background | This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin; actin; tropomyosin; myosin; and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase; and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.? |
| Synonyms | CDM; H-CAD; HCAD; L-CAD; LCAD; NAG22 |
| Reference Data | |
| Protein Pathways | Vascular smooth muscle contraction |
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