MYSM1 Rabbit Polyclonal Antibody
CAT＃: TA323309S
Anti-MYSM1 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1280.00
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CNY 300.00
CNY 1430.00
CNY 2900.00
CNY 6650.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 50-200 Positive control: Human ovarian cancer Predicted cell location: Nucleus |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 808-821 amino acids of Human Myb-like, SWIRM and MPN domains 1 |
| Isotype | IgG |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | Myb like, SWIRM and MPN domains 1 |
| Database Link | |
| Background | Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A; a specific tag for epigenetic transcriptional repression; thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.Component of a large chromatin remodeling complex; at least composed of MYSM1; PCAF; RBM10 and KIF11/TRIP5. Binds histones |
| Synonyms | 2A-DUB; 2ADUB |
| Reference Data | |
| Protein Families | Protease |
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