SERINC3 Rabbit Polyclonal Antibody
CAT＃: TA351654S
Rabbit Polyclonal Anti-SERINC3 Antibody
Size: 100 ul
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CNY 800.00
CNY 1280.00
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CNY 2900.00
CNY 6650.00
CNY 3080.00
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB: 200-1000 WB positive control: Human right and left lung cancer tissue IHC: 10-50 Positive control: Human brain Predicted cell location: Cytoplasm or Cell membrane |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human SERINC3 |
| Isotype | IgG |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 53 kDa |
| Gene Name | serine incorporator 3 |
| Database Link | |
| Background | TDE1, tumor differentially expressed protein 1, is a multi-pass membrane protein also known as serine incorporator 3. Also found on the membranes of the Golgi apparatus within cells, TDE1 is highly expressed in neuronal populations but is also found in thymus, kidney, liver and testis. Expression levels of TDE1 in tumors can be as much as tenfold the amount found in normal tissue of the same type. This increased expression implicates TDE1 as being involved in the cellular transformation from normal to malignant tissue. It is believed TDE1 contributes to oncogenesis by partially protecting cells from serum starvation and etoposide-induced apoptosis. |
| Synonyms | AIGP1; DIFF33; SBBI99; TDE; TDE1; TMS-1 |
| Reference Data | |
| Protein Families | Transmembrane |
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