Ribonuclease H2, subunit A (RNASEH2A) Mouse Monoclonal Antibody [Clone ID: OTI7H10]
CAT＃: TA815363S
RNASEH2A mouse monoclonal antibody,clone OTI7H10
Size: 100 ul
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Specifications
| Product Data | |
| Clone Name | OTI7H10 |
| Applications | WB |
| Recommend Dilution | WB 1:500-1:2000 |
| Reactivity | Human,Mouse |
| Host | Mouse |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human RNASEH2A (NP_006388) produced in E.coli. |
| Isotype | IgG1 |
| Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage Condition | Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws. |
| Predicted Protein Size | 33.4 kDa |
| Gene Name | ribonuclease H2 subunit A |
| Database Link | |
| Background | The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.[provided by RefSeq, Aug 2009] |
| Synonyms | AGS4; JUNB; RNASEHI; RNHIA; RNHL; THSD8 |
| Reference Data | |
| Protein Pathways | DNA replication |
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