Nlrp10 (NM_175532) Mouse Untagged Clone
CAT＃: MC220382
Nlrp10 (untagged) - Mouse NLR family, pyrin domain containing 10 (Nlrp10), (10ug)
CNY 8650.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 6430548I20Rik; Nalp10; Napl10; PAN5; Pynod |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC220382 representing NM_175532
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCCTTGGCACGGGCCAACAGCCCCCAGGAGGCACTGCTTTGGGCCTTGAATGACCTTGAGGAGAACA GTTTCAAGACGCTGAAGTTCCACTTACGAGATGTGACCCAATTTCATCTGGCCCGAGGGGAACTGGAGAG TCTGAGTCAGGTGGACCTGGCATCAAAACTGATTTCAATGTACGGAGCACAGGAAGCCGTGAGAGTGGTG AGCAGGAGCTTGCTGGCCATGAACTTGATGGAGCTTGTAGACTACCTCAACCAGGTTTGTCTGAATGATT ACAGAGAAATCTACCGGGAGCATGTGCGCTGCTTGGAGGAGAGGCAAGATTGGGGTGTTAATAGCAGCCA CAATAAGCTGCTCCTGATGGCCACATCCAGTTCAGGGGGTCGCAGATCACCTTCCTGTTCTGACCTGGAA CAGGAGTTGGATCCTGTCGATGTGGAGACTTTATTTGCTCCGGAGGCGGAGTCCTACTCAACCCCGCCCA TAGTGGTGATGCAAGGATCTGCGGGCACTGGAAAGACAACCCTGGTCAAAAAACTGGTGCAGGACTGGTC CAAAGGGAAGCTGTACCCAGGCCAGTTTGATTATGTTTTCTACGTGAGCTGCAGAGAAGTGGTCCTGTTA CCCAAGTGTGACCTGCCCAACCTCATCTGCTGGTGTTGTGGAGATGATCAAGCCCCAGTCACAGAGATTC TGCGGCAGCCTGGGCGGCTCCTGTTCATCCTGGATGGCTATGATGAGTTACAGAAGTCCAGTCGTGCCGA GTGCGTACTTCACATTCTGATGAGGAGAAGGGAGGTACCATGCTCCCTTCTCATCACCACGCGGCCTCCA GCTTTGCAGAGTCTGGAACCCATGTTGGGTGAACGGCGACATGTCCTTGTCTTAGGCTTCTCTGAGGAGG AGAGGGAAACATATTTCAGCTCCTGTTTTACGGATAAGGAGCAATTGAAAAATGCCCTTGAGTTTGTGCA AAACAATGCTGTTCTCTATAAAGCATGCCAGGTTCCAGGCATTTGCTGGGTGGTCTGCTCCTGGCTGAAG AAGAAGATGGCGAGAGGTCAGGAAGTCTCAGAGACACCTAGCAACAGTACAGACATCTTCACTGCTTATG TGTCCACCTTTCTGCCCACTGATGGCAATGGAGACAGCTCTGAGCTTACCAGGCACAAGGTACTGAAGAG TCTGTGCTCCTTGGCTGCGGAGGGGATGCGGCACCAGAGGCTGCTATTTGAAGAAGAGGTCCTCAGAAAG CATGGCTTAGACGGCCCCAGCCTTACTGCTTTCCTGAACTGCATCGACTACCGAGCGGGGCTTGGCATCA AGAAATTCTACAGCTTTCGCCACATCAGCTTCCAGGAATTTTTCTATGCCATGTCCTTCCTTGTGAAGGA GGACCAGAGTCAGCAGGGAGAGGCCACACACAAAGAAGTGGCAAAGCTGGTGGATCCAGAGAACCATGAA GAGGTGACTCTCAGTTTGCAGTTCTTATTCGACATGTTGAAAACAGAGGGCACCTTGAGCTTGGGGCTGA AGTTCTGCTTCAGAATCGCTCCTTCGGTAAGGCAGGATCTGAAGCATTTTAAAGAGCAAATAGAAGCCAT AAAGTACAAAAGGTCATGGGATCTGGAATTCTCTCTCTATGATTCTAAGATAAAGAAGCTCACACAAGGT ATCCAGATGAAAGATGTCATTCTCAATGTGCAACATTTGGATGAAAAGAAATCTGACAAGAAGAAGTCAG TTTCAGTGACAAGCAGCTTTAGTAGCGGGAAGGTACAAAGTCCATTCTTGGGAAATGATAAAAGCACCAG GAAACAAAAGAAGGCATCTAATGGGAAAAGCAGAGGGGCAGAGGAACCAGCCCCGGGGGTTAGAAACCGT AGGCTGGCAAGCAGAGAAAAGGGTCATATGGAGATGAATGATAAGGAGGATGGTGGGGTGGAGGAACAGG AGGATGAGGAAGGACAGACACTTAAAAAGGATGGAGAGATGATAGATAAGATGAATGGGTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_175532 |
| Insert Size | 2022 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_175532.3, NP_780741.1 |
| RefSeq Size | 4483 bp |
| RefSeq ORF | 2022 bp |
| Locus ID | 244202 |
| UniProt ID | Q8CCN1 |
| Gene Summary | Inhibits autoprocessing of CASP1, CASP1-dependent IL1B secretion, PYCARD aggregation and PYCARD-mediated apoptosis but not apoptosis induced by FAS or BID (By similarity). Displays anti-inflammatory activity (By similarity). Required for immunity against C.albicans infection (PubMed:23071280). Involved in the innate immune response by contributing to proinflammatory cytokine release in response to invasive bacterial infection (By similarity). Contributes to T-cell-mediated inflammatory responses in the skin (PubMed:27221772). Plays a role in protection against periodontitis through its involvement in induction of IL1A via ERK activation in oral epithelial cells infected with periodontal pathogens (By similarity). Exhibits both ATPase and GTPase activities (By similarity).[UniProtKB/Swiss-Prot Function] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG223786 | Nlrp10 (tGFP-tagged) - Mouse NLR family pyrin domain containing 10 (Nlrp10), (10ug) |
CNY 9008.00 |
|
| MR223786 | Nlrp10 (Myc-DDK-tagged) - Mouse NLR family, pyrin domain containing 10 (Nlrp10) |
CNY 7408.00 |
|
| MR223786L3 | Lenti ORF clone of Nlrp10 (Myc-DDK-tagged) - Mouse NLR family, pyrin domain containing 10 (Nlrp10) |
CNY 7890.00 |
|
| MR223786L4 | Lenti ORF clone of Nlrp10 (mGFP-tagged) - Mouse NLR family, pyrin domain containing 10 (Nlrp10) |
CNY 7890.00 |
