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Hspb6 (NM_001012401) Mouse Tagged ORF Clone
CAT＃: MR222204
- TrueORF®
Hspb6 (Myc-DDK-tagged) - Mouse heat shock protein, alpha-crystallin-related, B6 (Hspb6)
ORF Plasmid: tGFP
"NM_001012401" in other vectors (4)
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CNY 1,200.00
CNY 3,705.00
| Cited in 1 publication. |
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | AA387366; Gm479; Hsp20 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR222204 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) CTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCCGGCGC GCCC ATGGAGATCCCCGTGCCTGTGCAGCCTTCTTGGCTGCGCCGTGCTTCAGCTCCTTTACCAGGTTTCTCTG CTCCGGGACGCCTCTTTGACCAGCGTTTCGGCGAAGGGCTGCTTGAGGCAGAGCTGGCTTCACTGTGCCC TGCTGCGATCGCCCCCTACTATCTGCGCGCCCCCAGTGTGGCGTTACCCACAGCCCAGGTGTCCACGGAC TCTGGGTATTTTTCCGTGCTGCTGGATGTGAAGCACTTCTTGCCAGAGGAAATCTCTGTCAAGGTGGTTG ACGACCATGTGGAGGTCCATGCTCGGCACGAGGAGCGCCCGGATGAACACGGATTCATTGCTCGAGAGTT CCACCGCCGATACCGCCTGCCTCCTGGTGTGGACCCTGCTGCTGTGACCTCAGCACTGTCTCCTGAGGGT GTCCTGTCCATCCAGGCCACACCAGCGTCGGCCCAGGCCCAACTTCCGTCACCACCTGCTGCCAAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR222204 protein sequence
Red=Cloning site Green=Tags(s) MEIPVPVQPSWLRRASAPLPGFSAPGRLFDQRFGEGLLEAELASLCPAAIAPYYLRAPSVALPTAQVSTD SGYFSVLLDVKHFLPEEISVKVVDDHVEVHARHEERPDEHGFIAREFHRRYRLPPGVDPAAVTSALSPEG VLSIQATPASAQAQLPSPPAAK TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
AscI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001012401 |
| ORF Size | 489 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001012401.3 |
| RefSeq Size | 1383 bp |
| RefSeq ORF | 489 bp |
| Locus ID | 243912 |
| UniProt ID | Q5EBG6 |
| MW | 17.5 kDa |
| Gene Summary | Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state. Seems to have versatile functions in various biological processes. Plays a role in regulating muscle function such as smooth muscle vasorelaxation and cardiac myocyte contractility. May regulate myocardial angiogenesis implicating KDR. Overexpression mediates cardioprotection and angiogenesis after induced damage. Stabilizes monomeric YWHAZ thereby supporting YWHAZ chaperone-like activity.[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Loss of type 9 adenylyl cyclase triggers reduced phosphorylation of Hsp20 and diastolic dysfunction
,Li, Y;Baldwin, TA;Wang, Y;Subramaniam, J;Carbajal, AG;Brand, CS;Cunha, SR;Dessauer, CW;,
Sci Rep
,PubMed ID 28717248
[HSPB6]
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Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC213180 | Hspb6 (untagged) - Mouse heat shock protein, alpha-crystallin-related, B6 (Hspb6), (10ug) |
CNY 3,990.00 |
|
| MG222204 | Hspb6 (tGFP-tagged) - Mouse heat shock protein alpha-crystallin-related B6 (Hspb6), (10ug) |
CNY 2,850.00 |
|
| MR222204L3 | Lenti ORF clone of Hspb6 (Myc-DDK-tagged) - Mouse heat shock protein, alpha-crystallin-related, B6 (Hspb6) |
CNY 4,750.00 |
|
| MR222204L4 | Lenti ORF clone of Hspb6 (mGFP-tagged) - Mouse heat shock protein, alpha-crystallin-related, B6 (Hspb6) |
CNY 4,750.00 |
