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ADAMTS5 (NM_007038) Human Untagged Clone
CAT＃: SC115752
ADAMTS5 (untagged)-Human ADAM metallopeptidase with thrombospondin type 1 motif, 5 (ADAMTS5)
CNY 6,816.00
CNY 7,220.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ADAM-TS 5; ADAM-TS5; ADAM-TS 11; ADAMTS-5; ADAMTS-11; ADAMTS11; ADMP-2 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC115752 sequence for NM_007038 edited (data generated by NextGen Sequencing)
ATGCTGCTCGGGTGGGCGTCCCTGCTGCTGTGCGCGTTCCGCCTGCCCCTGGCCGCGGTC GGCCCCGCCGCGACACCTGCCCAGGATAAAGCCGGGCAGCCTCCGACTGCTGCAGCAGCC GCCCAGCCCCGCCGGCGGCAGGGGGAGGAGGTGCAGGAGCGAGCCGAGCCTCCCGGCCAC CCGCACCCCCTGGCGCAGCGGCGCAGGAGCAAGGGGCTGGTGCAGAACATCGACCAACTC TACTCCGGCGGCGGCAAGGTGGGCTACCTCGTCTACGCGGGCGGCCGGAGGTTCCTCTTG GACCTGGAGCGAGATGGTTCGGTGGGCATTGCTGGCTTCGTGCCCGCAGGAGGCGGGACG AGTGCGCCCTGGCGCCACCGGAGCCACTGCTTCTATCGGGGCACAGTGGACGGTAGTCCC CGCTCTCTGGCTGTCTTTGACCTCTGTGGGGGTCTCGACGGCTTCTTCGCGGTCAAGCAC GCGCGCTACACCCTAAAGCCACTGCTGCGCGGACCCTGGGCGGAGGAAGAAAAGGGGCGC GTGTACGGGGATGGGTCCGCACGGATCCTGCACGTCTACACCCGCGAGGGCTTCAGCTTC GAGGCCCTGCCGCCGCGCGCCAGCTGCGAAACCCCCGCGTCCACACCGGAGGCCCACGAG CATGCTCCGGCGCACAGCAACCCGAGCGGACGCGCAGCACTGGCCTCGCAGCTCTTGGAC CAGTCCGCTCTCTCGCCCGCTGGGGGCTCAGGACCGCAGACGTGGTGGCGGCGGCGGCGC CGCTCCATCTCCCGGGCCCGCCAGGTGGAGCTGCTTCTGGTGGCTGACGCGTCCATGGCG CGGTTGTATGGCCGGGGCCTGCAGCATTACCTGCTGACCCTGGCCTCCATCGCCAATAGG CTGTACAGCCATGCTAGCATCGAGAACCACATCCGCCTGGCCGTGGTGAAGGTGGTGGTG CTAGGCGACAAGGACAAGAGCCTGGAAGTGAGCAAGAACGCTGCCACCACACTCAAGAAC TTTTGCAAGTGGCAGCACCAACACAACCAGCTGGGAGATGACCATGAGGAGCACTACGAT GCAGCTATCCTGTTTACTCGGGAGGATTTATGTGGGCATCATTCATGTGACACCCTGGGA ATGGCAGACGTTGGGACCATATGTTCTCCAGAGCGCAGCTGTGCTGTGATTGAAGACGAT GGCCTCCACGCAGCCTTCACTGTGGCTCACGAAATCGGACATTTACTTGGCCTCTCCCAT GACGATTCCAAATTCTGTGAAGAGACCTTTGGTTCCACAGAAGATAAGCGCTTAATGTCT TCCATCCTTACCAGCATTGATGCATCTAAGCCCTGGTCCAAATGCACTTCAGCCACCATC ACAGAATTCCTGGATGATGGCCATGGTAACTGTTTGCTGGACCTACCACGAAAGCAGATC CTGGGCCCCGAAGAACTCCCAGGACAGACCTACGATGCCACCCAGCAGTGCAACCTGACA TTCGGGCCTGAGTACTCCGTGTGTCCCGGCATGGATGTCTGTGCTCGCCTGTGGTGTGCT GTGGTACGCCAGGGCCAGATGGTCTGTCTGACCAAGAAGCTGCCTGCGGTGGAAGGGACG CCTTGTGGAAAGGGGAGAATCTGCCTGCAGGGCAAATGTGTGGACAAAACCAAGAAAAAA TATTATTCAACGTCAAGCCATGGCAACTGGGGATCTTGGGGATCCTGGGGCCAGTGTTCT CGCTCATGTGGAGGAGGAGTGCAGTTTGCCTATCGTCACTGTAATAACCCTGCTCCCAGA AACAACGGACGCTACTGCACAGGGAAGAGGGCCATCTACCGCTCCTGCAGTCTCATGCCC TGCCCACCCAATGGTAAATCATTTCGTCATGAACAGTGTGAGGCCAAAAATGGCTATCAG TCTGATGCAAAAGGAGTCAAAACTTTTGTGGAATGGGTTCCCAAATATGCAGGTGTCCTG CCAGCGGATGTGTGCAAGCTGACCTGCAGAGCCAAGGGCACTGGCTACTATGTGGTATTT TCTCCAAAGGTGACCGATGGCACTGAATGTAGGCTGTACAGTAATTCCGTCTGCGTCCGG GGGAAGTGTGTGAGAACTGGCTGTGACGGCATCATTGGCTCAAAGCTGCAGTATGACAAG TGCGGAGTATGTGGAGGAGACAACTCCAGCTGTACAAAGATTGTTGGAACCTTTAATAAG AAAAGTAAGGGTTACACTGACGTGGTGAGGATTCCTGAAGGGGCAACCCACATAAAAGTT CGACAGTTCAAAGCCAAAGACCAGACTAGATTCACTGCCTATTTAGCCCTGAAAAAGAAA AACGGTGAGTACCTTATCAATGGAAAGTACATGATCTCCACTTCAGAGACTATCATTGAC ATCAATGGAACAGTCATGAACTATAGCGGTTGGAGCCACAGGGATGACTTCCTGCATGGC ATGGGCTACTCTGCCACGAAGGAAATTCTAATAGTGCAGATTCTTGCAACAGACCCCACT AAACCATTAGATGTCCGTTATAGCTTTTTTGTTCCCAAGAAGTCCACTCCAAAAGTAAAC TCTGTCACTAGTCATGGCAGCAATAAAGTGGGATCACACACTTCGCAGCCGCAGTGGGTC ACGGGCCCATGGCTCGCCTGCTCTAGGACCTGTGACACAGGTTGGCACACCAGAACGGTG CAGTGCCAGGATGGAAACCGGAAGTTAGCAAAAGGATGTCCTCTCTCCCAAAGGCCTTCT GCGTTTAAGCAATGCTTGTTGAAGAAATGTTAG Clone variation with respect to NM_007038.3 >OriGene 5' read for NM_007038 unedited
CCCATTTTGTAATACGACTTCACTATAGGGCGGCCGCGAATTCGCACGAGCAGACACGCC GCTTCACCAGCTCGCCTCAGGCTGCCCCCCTGCATTTTTGTTTTAATTTTTACGGCTTTT TCCCCTCTCTTTCTTCCCTTCCTCCTGGTCCCAGCAGAGCCAAGGAAACCCACAAAATAA GAAAGGAAGTGGGCCCCGGAGCTTGGAACCTCCACAGCCGGCTTGTCCAGCGCAGCGCGG GGGCGGGAGGCTGCGCGCACCAGTTGCCAGCCCGGTGCGCGGTACCTTTCCTTACTTTTC TTGAAACAGCGATCGTGCCTGCATTTGGTGGTTTTTTGGTTTTTGTTTTTTTCCTTTTCC CGTATTTGCTGAATCTCCACTATCCGACTTTTTTTTTTTAATCTTTTCTTTCCCCCCCCC CACCCCACCTCTTTCTGGAGCACGAATCCAAACATTTTCCCAAGCAACAAAGAAAAGTTC GCACGCTGGCACCGCAGCCCGGACAGGCTGGCGCTGCTGCCGGGCCCCCCTCCCTCCGAC ACTTGACTCAATCCTGCAAGCAAGTGTGTGTGTGTCCCCATCCCCCGCCCCGTTAACTTC ATAGCAAATAACAAATACCCATAAAGTCCCAGTCGCGCAGCCCCTCCCCGCGGGCAGCGC ACTATGCTGCTCGGGTGGGCGTCCCTGCTGCTGTGCGCGTTCCGCCTGCCCCTGGCCGCG GTCGGCCCCGCCGCGACACCTGCCCAGGATAAAGCCGGCAGCCTCCGACTGCTGCAGCAG CCGCCCACCCCCCCGGCGGCAGGGGGAAGAAGTGCAAGANCGAGCCNAGCCTNCCGGCCA CCCGCACCCCTGGCGCANCGGCGCAGAGCAGGGGCTGGTGCAGACATCGACAACTCTACT CGGCGCGGCAAGTGGGCTAACTGTCTAGCGGGCGGCGGGGTTCTCTTGACCTGACGGATG TT >OriGene 3' read for NM_007038 unedited
ATCGAAGTTTTTTTTCTTTTTTTTTTTATAGAAATTATATGGGTATTTTAATAGAACCAG GGGATATAAAGTGACATACCAAGGGAGAATGTATTTACAAACAGTAAGAAGAAGCTACTG TGTATTATGGGTGAAAATGATTATGATACCATTAAAGACATTCTATCAGAGGTAGGTGAC AAGGGGGAGACAGTTCTGCCATCTTCAAATGTCCCCTGATTTTACATTCATCAGTGTTTC TTGTAAGCCCAGGGGATGTTCAATAACTCCCAAGTTTTTCTATATTGCAAGGTCACCACT GTCACGTGAAGCAGTGCACATCCTCTTTTGGTCACAGAGAGCAGATTCTGCCCATAATTG GACTCCTGTTGACAATGTCACTGAAGCATGACTTTCTGTGCGTTAGGTAGACCTCCTGTT CACCACGACTGCATCAGTGCTGAATCCTCCAGTTATCTTTGTGCATAAGATCATAACCAC AGGCTAACATTTCTTCAACAAGCATTGCTTANACGCAGAAGGCCTTTGGGAGAGAGGACA TCCTTTTGCTAACTTNCGGTTTCCATCCTGGCACTGCACCGTTCNTGGTGTGCCAAACCT GTGTCACAGGTCCTAGAGCAGGCGAGCCATGGGCCCGTGACCCACTGCGGCTGCGAAGTG TGTGATCCCACTTTATTGCTGNCATGACTAGTGACAGAGTTTACTTTTGGAGTGGACTTC CTGGGGACCAAAAAGCTATTACGGAACTCTAAGGGTTTATGGGGGTCCTGTTGCAGAATT CTGCACTATTAAAATTTCCTTCGCGGGCCNGATTACCCCCTCCCATGCCAGAAAGTCCTC CCCTGTG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_007038 |
| Insert Size | 4000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_007038.2, NP_008969.1 |
| RefSeq Size | 9046 bp |
| RefSeq ORF | 2793 bp |
| Locus ID | 11096 |
| UniProt ID | Q9UNA0 |
| Domains | tsp_1, Reprolysin, ACR |
| Protein Families | Druggable Genome, Protease, Secreted Protein |
| Gene Summary | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis. [provided by RefSeq, Feb 2016] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Lost expression of ADAMTS5 protein associates with progression and poor prognosis of hepatocellular carcinoma
,Li, C;Xiong, Y;Yang, X;Wang, L;Zhang, S;,
Drug Design, Development and Therapy
[ADAMTS5]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210834 | ADAMTS5 (Myc-DDK-tagged)-Human ADAM metallopeptidase with thrombospondin type 1 motif, 5 (ADAMTS5) |
CNY 3,990.00 |
|
| RC210834L1 | Lenti ORF clone of Human ADAM metallopeptidase with thrombospondin type 1 motif, 5 (ADAMTS5), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210834L2 | Lenti ORF clone of Human ADAM metallopeptidase with thrombospondin type 1 motif, 5 (ADAMTS5), mGFP tagged |
CNY 5,890.00 |
|
| RC210834L3 | Lenti ORF clone of Human ADAM metallopeptidase with thrombospondin type 1 motif, 5 (ADAMTS5), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210834L4 | Lenti ORF clone of Human ADAM metallopeptidase with thrombospondin type 1 motif, 5 (ADAMTS5), mGFP tagged |
CNY 5,890.00 |
|
| RG210834 | ADAMTS5 (tGFP-tagged) - Human ADAM metallopeptidase with thrombospondin type 1 motif, 5 (ADAMTS5) |
CNY 4,370.00 |
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