ERCC6L (BC008808) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	PICH; RAD26L
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC008808 edited CCACCTTGCAAGATGGTAAAGGTACAGGTAGTGCTGACTCTATAGCTACTTTACCAAAGG GGTTTGGAAGTGTAGAAGAACTTTGTACTAACTCTTCATTGGGAATGGAAAAAAGCTTTG CAACTAAAAATGAAGCTGTACAAAAAGAGACATTACAAGAGGGGCCTAAGCAAGAGGCAC TGCAAGAGGATCCTCTGGAAAGTTTTAATTATGTACTTAGCAAATCAACCAAAGCTGATA TTGGGCCAAATTTAGATCAACTAAAGGATGATGAGATTTTACGTCATTGCAATCCTTGGC CCATTATTTCCATAACAAATGAAAGTCAAAATGCAGAATCAAATGTATCCATTATTGAAA TAGCTGATGACCTTTCAGCATCCCATAGTGCACTGCAGGATGCTCAAGCAAGTGAGGCCA AGTTGGAAGAGGAACCTTCAGCATCTTCACCACAGTATGCATGTGATTTCAATCTTTTCT TGGAAGACTCAGCAGACAACAGACAAAATTTTTCCAGTCAGTCTTTAGAGCATGTTGAGA AAGAAAATAGCTTGTGTGGCTCTGCACCTAATTCCAGAGCAGGGTTTGTGCATAGCAAAA CATGTCTCAGTTGGGAGTTTTCTGAGAAAGACGATGAACCAGAAGAAGTAGTAGTTAAAG CAAAAATCAGAAGTAAAGCTAGAAGGATTGTTTCAGATGGCGAAGATGAAGATGATTCTT TTAAAGATACCTCAAGCATAAATCCATTCAACACATCTCTCTTTCAATTCTCATCTGTGA AACAATTTGATGCTTCAACTCCCAAAAATGACATCAGTCCACCAGGAAGGTTCTTTTCAT CTCAAATACCCAGTAGTGTAAATAAGTCTATGAACTCTAGAAGATCTCTGGCTTCTAGGA GGTCTCTTATTAATATGGTTTTAGACCACGTGGAGGACATGGAGGAAAGACTTGACGACA GCAGTGAAGCAAAGGGTCCTGAAGATTATCCAGAAGAAGGGGTGGAGGAAAGCAGTGGCG AAGCCTCCAAGTATACAGAAGAGGATCCTTCCGGAGAAACACTGTCTTCAGAAAACAAGT CCAGCTGGTTAATGACGTCTAAGCCTAGTGCTCTAGCTCAAGAGACCTCTCTTGGTGCCC CTGAGCCTTTGTCTGGTGAACAGTTGGTTGGTTCTCCCCAGGATAAGGCGGCAGAGGCTA CAAATGACTATGAGACTCTTGTAAAGCGTGGAAAAGAACTAAAAGAGTGTGGAAAAATCC AGGAGGCCCTAAACTGCTTAGTTAAAGCGCTTGACATAAAAAGTGCAGATCCTGAAGTTA TGCTCTTGACTTTAAGTTTGTATAAGCAACTTAATAACAATTGAGAATGTAACCTGTTTA TTGTATTTTAAAGTGAAACTGAATATGAGGGAATTTTTGTTCCCATAATTGGATTCTTTG GGAACATGAAGCATTCAGGCTTAAGGCAAGAAAGATCTCAAAAAGCAACTTCTGCCCTGC AACGCCCCCCACTCCATAGTCTGGTATTCTGAGCACTAGCTTAATATTTCTTCACTTGAA TATTCTTATATTTTAGGCATATTCTATAAATTTAACTGTGTTGTTTCTTGGAAAGTTTTG TAAAATTATTCTGGTCATTCTTAATTTTACTCTGAAAGTGATCATCTTTGTATATAACAG TTCAGATAAGAAAATTAAAGTTACTTTTCTCAAAAAAAAAAAAAAAAAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC008808 unedited NGGGGAGTTTAGGATTTGTAATACGACTTATATAGGCGGCCGCGCAATTCGCACGAGGCC ACCTTGCAAGATGGTAAAGGTACAGGTAGTGCTGACTCTATAGCTACTTTACCAAAGGGT TTGGAAGTGTAGAAGAACTTTGTACTAACTCTTCATTGGGAATGGAAAAAAGCTTTGCAA CTAAAAATGAAGCTGTACAAAAAGAGACATTACAAGAGGGGCCTAAGCAAGAGGCACTGC AAGAGGATCCTCTGGAAAGTTTTAATTATGTACTTAGCAAATCAACCAAAGCTGATATTG GGCCAAATTTAGATCAACTAAAGGATGATGAGATTTTACGTCATTGCAATCCTTGGCCCA TTATTTCCATAACAAATGAAAGTCAAAATGCAGAATCAAATGTATCCATTATTGAAATAG CTGATGACCTTTCAGCATCCCATAGTGCACTGCAGGATGCTCAAGCAAGTGAGGCCAAGT TGGAAGAGGAACCTTCAGCATCTTCACCACAGTATGCATGTGATTTCAATCTTTTCTTGG AAGACTCAGCAGACAACAGACAAAATTTTTCCAGTCAGTCTTTAGAGCATGTTGAGAAAG AAAATAGCTTGTGTGGCTCTGCACCTAATTTCAGAGCANGGTTTGTGCATAGCAAAACAT GTCTCAGTTGGGAGTTTTCTGAGNAAGACGATGAACCAGAAGAGTAGTAGTTAAAGCGAA AAATCAGAGTAAAGCTAGAAGGATTGTTTCAGATGGCGAAGATGAAGATGATTCTTTTAA AGATACCTCAAGCATAAATCCATTCAACACATCTCTCTTTCATTCTCATCTGTGAAACAT TTGATGCTCAACTCCCAAAATGACATCAGTCCACAGGAAGGTGCTTTCAT
Restriction Sites	Please inquire
ACCN	BC008808
Insert Size	1738 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	BC008808.2, AAH08808.2
RefSeq Size	1729 bp
Locus ID	54821
Gene Summary	This gene encodes a member of the SWItch/Sucrose Non-Fermentable (SWI/SNF2) family of proteins, and contains a SNF2-like ATPase domain and a PICH family domain. One distinguishing feature of this SWI/SNF protein family member is that during interphase, the protein is excluded from the nucleus, and only associates with chromatin after the nuclear envelope has broken down. This protein is a DNA translocase that is thought to bind double-stranded DNA that is exposed to stretching forces, such as those exerted by the mitotic spindle. This protein associates with ribosomal DNA and ultra-fine DNA bridges (UFBs), fine structures that connect sister chromatids during anaphase at some sites such as fragile sites, telomeres and centromeres. This gene is required for the faithful segregation of sister chromatids during mitosis, and the ATPase activity of this protein required for the resolution of UFBs before cytokinesis. [provided by RefSeq, May 2017]

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