RGS7 (NM_002924) Human Untagged Clone
CAT＃: SC127265
RGS7 (untagged)-Human regulator of G-protein signaling 7 (RGS7)
CNY 3656.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_002924, the custom clone sequence may differ by one or more nucleotides
ATGGCCCAGGGGAATAATTATGGGCAGACCAGCAACGGGGTGGCCGATGAATCACCCAACATGCTGGTGT ACAGAAAGATGGAAGACGTCATAGCACGGATGCAAGATGAAAAAAATGGAATTCCTATTCGTACGGTCAA AAGCTTTCTTTCCAAGATACCTAGCGTCTTCTCTGGTTCAGACATTGTTCAATGGTTGATAAAGAACTTA ACTATAGAAGATCCAGTGGAGGCGCTCCATTTGGGAACATTAATGGCTGCCCACGGCTACTTCTTTCCAA TCTCAGATCATGTCCTCACACTCAAGGATGATGGCACCTTTTACCGGTTTCAAACCCCCTATTTTTGGCC ATCAAATTGTTGGGAGCCGGAAAACACAGATTATGCCGTTTACCTCTGCAAGAGAACAATGCAAAACAAG GCACGACTGGAGCTCGCAGACTATGAGGCTGAGAGCCTGGCCAGGCTGCAGAGAGCATTTGCCCGGAAGT GGGAGTTCATTTTCATGCAAGCAGAAGCACAAGCAAAAGTGGACAAGAAGAGAGACAAGATTGAAAGGAA GATCCTTGACAGCCAAGAGAGAGCGTTCTGGGACGTGCACAGGCCCGTGCCTGGATGTGTAAATACAACT GAAGTGGACATTAAGAAGTCATCCAGAATGAGAAACCCCCACAAAACACGGAAGTCTGTCTATGGTTTAC AAAATGATATTAGAAGTCACAGTCCTACCCACACACCCACACCAGAAACTAAACCTCCAACAGAAGATGA GTTACAACAACAGATAAAATATTGGCAAATACAGTTAGATAGACATCGGTTAAAAATGTCAAAAGTCGCT GACAGTCTACTAAGTTACACGGAACAGTATTTAGAATACGACCCGTTTCTTTTGCCACCTGACCCTTCTA ACCCATGGCTGTCCGATGACACCACTTTCTGGGAACTTGAGGCAAGCAAAGAACCGAGCCAGCAGAGGGT AAAACGATGGGGTTTTGGCATGGACGAGGCATTGAAAGACCCAGTTGGGAGAGAACAGTTCCTTAAATTT CTAGAGTCAGAATTCAGCTCGGAAAATTTAAGATTCTGGCTGGCAGTGGAGGACCTGAAAAAGAGGCCTA TTAAAGAAGTACCCTCAAGAGTTCAGGAAATATGGCAAGAGTTTCTGGCTCCCGGAGCCCCCAGTGCTAT TAACTTGGATTCCAAGAGTTATGACAAAACCACACAGAACGTGAAGGAACCTGGACGATACACATTTGAA GATGCTCAGGAGCACATTTACAAACTGATGAAAAGTGATTCATACCCACGTTTTATAAGATCCAGTGCCT ATCAGGAGCTTCTACAGGCAAAGAAAAAGTCTGGAAACTCAATGGATCGCAGAACATCTTTTGAAAAATT TGCACAGAATGTGGGGAAATCTCTCACGTCCAAGAGGTTAACAAGCCTTGCTCAGTCTTACTAA >OriGene 5' read for NM_002924 unedited
CGACTCACTATAGGCGGCCGCGATTCGGCACGAGGGCGAGGCGAGGGTGGCGGTCGCCTG AGCAGCTAGAGCCGGGGCGGCGCGGAATCCGCATCCGCCGCGAGTGTGATGAAGCTACCC TGCCTCGCTGCTCCGCTTGCCGCCAGCTGACACCGCCTGCACCCAGCCCGCCCGGGAGGG GAGACGCCGCGGGGCCGTGACCTTGGCGGAGGAGGGCACACTGATAATTCTTGTATCTTG AGTGTGGACCAAGTTTTGGGTGACATGGCCCAGGGGAATAATTATGGGCAGACCAGCAAC GGGGTGGCCGATGAATCACCCAACATGCTGGTGTACAGAAAGATGGAAGACGTCATAGCA CGGATGCAAGATGAAAAAAATGGAATTCCTATTCGTACGGTCAAAAGCTTTCTTTCCAAG ATACCTAGCGTCTTCTCTGGTTCAGACATTGTTCAATGGTTGATAAAGAACTTAACTATA GAAGATCCAGTGGAGGCGCTCCATTTGGGAACATTAATGGCTGCCCACGGCTACTTCTTT CCAATCTCAGATCATGTCCTCACACTCAAGGATGATGGCACCTTTTACCGGTTTCAAACC CCCTATTTTTGGCCATCAAATTGTTGGGAGCCCGANAACACAGATTATGCCGTTTACCTC TGCAAGAGAACATGCANAACAGGCACGACTGGAGCTCGCAGACTATGAGGCTGAGAGCCT GGCCAGGCTGCAGAGAGCATTTGCCCGGGAGTGGGGAGTCATTTTCATGCCAGCAGAAGC ACCAGCAAAGTGGGACAGAAGAAGACAGATTGAAGGNAGATCCTGACGNCAGAGAGAGCG TCTGGGACGTGCCAGGCNCGTGCCTGGATGTGTAATACACTGAAGTGCATTNAGAGTCAT CGATGAGAACCCCACAACACGNAGCTGNCTATGTTACAATGTATAGAGTACAGTCTACCC CACCACCCAGAACTACTCACGG >OriGene 3' read for NM_002924 unedited
CCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTGAGATTCTGCATCTTTTAAT GAAAGATAAAACAACAATATAAACATACACAAATTTACAGAGAAGGGATCAACTTTAATA CATTTGGAGTAAAAGGGGTTTCTTCTTTAAATATGGTATAAAAATAAATGCGAGAAACAT TAACGGAGAATGTACAGACAACAGACGAAGACATGAGTTTGTTTCTGACTGTGACACATT GGTGAAATGAAACTTTCTGTGCGGAATTTATTGTTTAATAAATGTGAAGCCACATGTATA CTTATTGATATATACTTTTTTCTTTTACAATTCTTCCAGTTTTTGACTGACTGAATTTTC AGTGAACTGTGTGTCTAGCTGAAGCTTTGAGAGAGAGAGAGAGAGAAAGAAGGAAAAAAA GAAAAGGTTTTACTTCACTTGAACTTGTTAAAAAGGAAGAGACACAGATCCAGCATAGTA GAAGGAGAAAGAAAGCAGACAACAGTTTGGAATGGAGGCATTGAGACGGAAGAGTCCATT GGAGATGGAATGTACACACCAAAAATAACAATTTAAGTCCTTTGCTCATGCAACATCTTG GTCTAATGTCCTCTGCTTCCAGTCACAACATTGAGCTACAAGTGTGTGCAGGGACTTCAG CCTGCATTCATGCTACCAGAAGATCCGTTTAGTAAGACTGACCAAGGCTTTGTTAACCTC TTGGACGTGAGAGATTTCCCCTCTTTTCATAACAGGTTACGGCTGGCCCCTCACGGCGGG GTAACACGTTTTAGGGCATGGGAAATACGGATGTTTTTGCCTTTCTCTTTGCCTGAAAAA CTCCTGAAAGGCCTGGACCTATAAAACCGGGGTTGAATCACTTTCACCACTCTGAAAAGG GCTCCTGACACTTCAAAGGGGATTGCCAAGTCCTTCCCTCTGGGGGGTTCGCAAACCCCT GGAACAAGTTATAGACTGGGGCCCCGGGACCCAAAT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002924 |
| Insert Size | 2390 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002924.2, NP_002915.2 |
| RefSeq Size | 2408 bp |
| RefSeq ORF | 1464 bp |
| Locus ID | 6000 |
| UniProt ID | P49802 |
| Domains | RGS, DEP, G-gamma |
| Protein Families | Druggable Genome |
| Gene Summary | Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:10521509, PubMed:10862767). The RGS7/GNB5 dimer enhances GNAO1 GTPase activity (PubMed:10521509). May play a role in synaptic vesicle exocytosis (PubMed:12659861). Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling (PubMed:15897264).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) encodes isoform 1. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205284 | RGS7 (Myc-DDK-tagged)-Human regulator of G-protein signaling 7 (RGS7) |
CNY 3656.00 |
|
| RC205284L1 | Lenti ORF clone of Human regulator of G-protein signaling 7 (RGS7), Myc-DDK-tagged |
CNY 5890.00 |
|
| RC205284L2 | Lenti ORF clone of Human regulator of G-protein signaling 7 (RGS7), mGFP tagged |
CNY 6056.00 |
|
| RC205284L3 | Lenti ORF clone of Human regulator of G-protein signaling 7 (RGS7), Myc-DDK-tagged |
CNY 5890.00 |
|
| RC205284L4 | Lenti ORF clone of Human regulator of G-protein signaling 7 (RGS7), mGFP tagged |
CNY 5890.00 |
|
| RG205284 | RGS7 (tGFP-tagged) - Human regulator of G-protein signaling 7 (RGS7) |
CNY 5256.00 |
