Human eRF1 (ETF1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ETF1
Locus ID	2107
Kit Components	GA101466G1, eRF1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101466G2, eRF1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101466G3, eRF1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001256302, NM_001282185, NM_001291974, NM_001291975, NM_004730, NR_045992, NR_045994, NM_001364160, NR_157090
Synonyms	D5S1995; ERF; ERF1; RF1; SUP45L1; TB3-1
Summary	This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X. [provided by RefSeq, Aug 2013]

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