Human RAIDD (CRADD) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CRADD
Locus ID	8738
Kit Components	GA105802G1, RAIDD gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105802G2, RAIDD gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105802G3, RAIDD gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001320099, NM_001320100, NM_001320101, NM_001330126, NM_003805, NR_135147
Synonyms	MRT34; RAIDD
Summary	This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

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