Human MTRF1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MTRF1
Locus ID	9617
Kit Components	GA106439G1, MTRF1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106439G2, MTRF1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106439G3, MTRF1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_004294, NM_001354073, NM_001354074, NM_001354075, NM_001354076
Synonyms	MRF1; MTTRF1; RF1
Summary	The protein encoded by this gene was determined by in silico methods to be a mitochondrial protein with similarity to the peptide chain release factors (RFs) discovered in bacteria and yeast. The peptide chain release factors direct the termination of translation in response to the peptide chain termination codons. Initially thought to have a role in the termination of mitochondria protein synthesis, a recent publication found no mitochondrial translation release functionality. Multiple alternatively spliced transcript variants have been suggested by mRNA and EST data; however, their full-length natures are not clear. [provided by RefSeq, Jul 2008]

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