Human TIP30 (HTATIP2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HTATIP2
Locus ID	10553
Kit Components	GA107213G1, TIP30 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107213G2, TIP30 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107213G3, TIP30 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001098520, NM_001098521, NM_001098522, NM_001098523, NM_006410
Synonyms	CC3; SDR44U1; TIP30
Summary	Oxidoreductase required for tumor suppression. NAPDH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect.[UniProtKB/Swiss-Prot Function]

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