Human WIPI2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	WIPI2
Locus ID	26100
Kit Components	GA108753G1, WIPI2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108753G2, WIPI2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108753G3, WIPI2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001033518, NM_001033519, NM_001033520, NM_001278299, NM_015610, NM_016003
Synonyms	ATG18B; Atg21; CGI-50; WIPI-2
Summary	WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).[supplied by OMIM, Mar 2008]

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