Human ZNF313 (RNF114) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RNF114
Locus ID	55905
Kit Components	GA111052G1, ZNF313 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111052G2, ZNF313 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111052G3, ZNF313 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_018683
Synonyms	PSORS12; ZNF313
Summary	E3 ubiquitin-protein ligase promoting the ubiquitination and degradation of the CDK inhibitor CDKN1A and probably also CDKN1B and CDKN1C. These activities stimulate cell cycle's G1-to-S phase transition and suppress cellular senescence. May play a role in spermatogenesis.[UniProtKB/Swiss-Prot Function]

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