Human CCDC90A (MCUR1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MCUR1
Locus ID	63933
Kit Components	GA111925G1, CCDC90A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111925G2, CCDC90A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111925G3, CCDC90A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001031713, NM_022102
Synonyms	C6orf79; CCDC90A; FMP32
Summary	Key regulator of mitochondrial calcium uniporter (MCU) required for calcium entry into mitochondrion (PubMed:23178883, PubMed:26445506, PubMed:27184846, PubMed:26976564). Plays a direct role in uniporter-mediated calcium uptake via a direct interaction with MCU (PubMed:23178883). Probably involved in the assembly of the membrane components of the uniporter complex (uniplex) (PubMed:27184846).[UniProtKB/Swiss-Prot Function]

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