Human FAM83D activation kit by CRISPRa
CAT#: GA113088
FAM83D CRISPRa kit - CRISPR gene activation of human family with sequence similarity 83 member D
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | FAM83D |
Locus ID | 81610 |
Kit Components | GA113088G1, FAM83D gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113088G2, FAM83D gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113088G3, FAM83D gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_030919 |
Synonyms | C20orf129; CHICA; dJ616B8.3 |
Summary | Probable proto-oncogene that regulates cell proliferation, growth, migration and epithelial to mesenchymal transition. Through the degradation of FBXW7, may act indirectly on the expression and downstream signaling of MTOR, JUN and MYC (PubMed:24344117). May play also a role in cell proliferation through activation of the ERK1/ERK2 signaling cascade (PubMed:25646692). May also be important for proper chromosome congression and alignment during mitosis through its interaction with KIF22.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN416954 | FAM83D - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |