Human NLRP8 activation kit by CRISPRa

CAT#: GA114922

NLRP8 CRISPRa kit - CRISPR gene activation of human NLR family pyrin domain containing 8



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CNY 12255.00


货期*
4周

规格
    • 1 kit

Product images

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol NLRP8
Locus ID 126205
Kit Components

GA114922G1, NLRP8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA114922G2, NLRP8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA114922G3, NLRP8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_001317000, NM_176811
Synonyms CLR19.2; NALP8; NOD16; PAN4
Summary This gene encodes a member of the nucleotide-binding oligomerization domain/ leucine rich repeat/ pyrin domain containing (NLRP) subfamily, which belongs to the Nod-like receptor family of proteins. NLRP genes play roles in the mammalian innate immune system through inflammasome formation and activation of caspases. In addition, NLRP genes have been found to function during mammalian reproduction. Consistent with a function during human preimplantation development, this gene is expressed at high levels in oocytes with decreased levels in embryos. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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