Human C8orf80 (NUGGC) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NUGGC
Locus ID	389643
Kit Components	GA118064G1, C8orf80 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA118064G2, C8orf80 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA118064G3, C8orf80 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001010906
Synonyms	C8orf80; HMFN0672; SLIP-GC
Summary	Nuclear GTPase found in germinal center B-cells, where it may inhibit function of the activation-induced cytidine deaminase AICDA (PubMed:19734146). Reduces somatic hypermutation in B-cells which may enhance genome stability (By similarity).[UniProtKB/Swiss-Prot Function]

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