Mouse Ciita activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ciita
Locus ID	12265
Kit Components	GA200464G1, Ciita gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200464G2, Ciita gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200464G3, Ciita gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001243760, NM_001243761, NM_001302618, NM_001302619, NM_007575
Synonyms	C2ta; EG669998; Gm9475; Mhc2ta
Summary	This gene encodes a member of the NOD-like receptor protein family. This protein acts as a transcriptional coactivator and component of the enhanceosome complex to stimulate transcription of MHC class II genes in the adaptive immune response. This protein may also regulate the transcription of MHC class I genes. Mutations in the human gene have been linked to a rare immunodeficiency, bare lymphocyte syndrome, and homozygous knockout mice exhibit many features of this disease. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]

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