DYNLRB1 (NM_014183) Human Mass Spec Standard

Specifications

Product Data
Description	DYNLRB1 MS Standard C13 and N15-labeled recombinant protein (NP_054902)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC200051
Predicted MW	10.9 kDa
Protein Sequence	Sequence Link (showhide) >RC200051 protein sequence Red=Cloning site Green=Tags(s) MAEVEETLKRLQSQKGVQGIIVVNTEGIPIKSTMDNPTTTQYASLMHSFILKARSTVRDIDPQNDLTFLR IRSKKNEIMVAPDKDYFLIVIQNPTE TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_054902
RefSeq Size	717
RefSeq ORF	288
Synonyms	BITH; BLP; DNCL2A; DNLC2A; ROBLD1
Locus ID	83658
Cytogenetics	20q11.22
Summary	This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18. [provided by RefSeq, Aug 2013]

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