Cortactin (CTTN) (NM_138565) Human Mass Spec Standard
CAT＃: PH301111
CTTN MS Standard C13 and N15-labeled recombinant protein (NP_612632)
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CNY 19520.00
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Specifications
| Product Data | |
| Description | CTTN MS Standard C13 and N15-labeled recombinant protein (NP_612632) |
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC201111 |
| Predicted MW | 57.5 kDa |
| Protein Sequence |
>RC201111 protein sequence
Red=Cloning site Green=Tags(s) MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRENVFQEHQTLK EKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRGFGGKFGVQMDRVDQSAVGFE YQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQGKTEKHESQRDYSKGFGGKYGIDKDKVDKSA VGFEYQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKLQLHESQKDYSKGFGGKYGVQKDRM DKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKEKEQEDRRKAEAERAQRMAKERQEQEEA RRKLEEQARAKTQTPPVSPAPQPTEERLPSSPVYEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREAS SQQGLAYATEAVYESAEAPGHYPAEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDD GWWRGVCKGRYGLFPANYVELRQ TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Reference Data | |
| RefSeq | NP_612632 |
| RefSeq Size | 3208 |
| RefSeq ORF | 1539 |
| Synonyms | EMS1 |
| Locus ID | 2017 |
| Cytogenetics | 11q13.3 |
| Summary | This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010] |
| Protein Families | Druggable Genome |
| Protein Pathways | Pathogenic Escherichia coli infection, Tight junction |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC403359 | CTTN HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
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| LC417430 | CTTN HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1470.00 |
|
| LC429248 | CTTN HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY403359 | Transient overexpression lysate of cortactin (CTTN), transcript variant 2 |
CNY 3080.00 |
|
| LY417430 | Transient overexpression lysate of cortactin (CTTN), transcript variant 1 |
CNY 4840.00 |
|
| LY429248 | Transient overexpression lysate of cortactin (CTTN), transcript variant 1 |
CNY 3080.00 |
|
| TP301111 | Recombinant protein of human cortactin (CTTN), transcript variant 2, 20 µg |
CNY 2900.00 |
|
| TP710315 | Purified recombinant protein of Human cortactin (CTTN / EMS1), transcript variant 2, full length, with C-terminal DDK tag, expressed in sf9, 20ug |
CNY 4020.00 |
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