Optineurin (OPTN) (NM_001008211) Human Mass Spec Standard

CAT#: PH302470

OPTN MS Standard C13 and N15-labeled recombinant protein (NP_001008212)



  View other "Optineurin" proteins (13)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of optineurin (OPTN), transcript variant 1
    • 100 ug

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OPTN mouse monoclonal antibody,clone OTI7H2
    • 100 ul

CNY 1,999.00
CNY 2,700.00

Specifications

Product Data
Description OPTN MS Standard C13 and N15-labeled recombinant protein (NP_001008212)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC202470
Predicted MW 65.9 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001008212
RefSeq Size 3597
RefSeq ORF 1731
Synonyms ALS12; FIP2; GLC1E; HIP7; HYPL; NRP; TFIIIA-INTP
Locus ID 10133
Cytogenetics 10p13
Summary This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
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