C3Orf34 (CEP19) (NM_032898) Human Mass Spec Standard

Specifications

Product Data
Description	C3orf34 MS Standard C13 and N15-labeled recombinant protein (NP_116287)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC203186
Predicted MW	19.2 kDa
Protein Sequence	Sequence Link (showhide) >RC203186 protein sequence Red=Cloning site Green=Tags(s) MMCTAKKCGIRFQPPAIILIYESEIKGKIRQRIMPVRNFSKFSDCTRAAEQLKNNPRHKSYLEQVSLRQL EKLFSFLRGYLSGQSLAETMEQIQRETTIDPEEDLNKLDDKELAKRKSIMDELFEKNQKKKDDPNFVYDI EVEFPQDDQLQSCGWDTESADEF TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_116287
RefSeq Size	2216
RefSeq ORF	489
Synonyms	C3orf34; MOSPGF
Locus ID	84984
Cytogenetics	3q29
Summary	The protein encoded by this gene localizes to centrosomes and primary cilia and co-localizes with a marker for the mother centriole. This gene resides in a region of human chromosome 3 that is linked to morbid obesity. A homozygous knockout of the orthologous gene in mouse resulted in mice with morbid obesity, hyperphagy, glucose intolerance, and insulin resistance. Mutations in this gene cause morbid obesity and spermatogenic failure (MOSPGF). This gene has a pseudogene on human chromosome 2. [provided by RefSeq, Apr 2014]

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