SIKE1 (NM_025073) Human Mass Spec Standard

Specifications

Product Data
Description	SIKE1 MS Standard C13 and N15-labeled recombinant protein (NP_079349)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC203262
Predicted MW	23.7 kDa
Protein Sequence	Sequence Link (showhide) >RC203262 protein sequence Red=Cloning site Green=Tags(s) MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKDMSKYKPH ILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIES QIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESLQARKENSMDTASQAIK TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_079349
RefSeq Size	5507
RefSeq ORF	621
Synonyms	SIKE
Locus ID	80143
Cytogenetics	1p13.2
Summary	SIKE interacts with IKK-epsilon (IKBKE; MIM 605048) and TBK1 (MIM 604834) and acts as a suppressor of TLR3 (MIM 603029) and virus-triggered interferon activation pathways (Huang et al., 2005 [PubMed 16281057]).[supplied by OMIM, Mar 2008]
Protein Pathways	RIG-I-like receptor signaling pathway

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