HE4 (WFDC2) (NM_006103) Human Mass Spec Standard

Specifications

Product Data
Description	WFDC2 MS Standard C13 and N15-labeled recombinant protein (NP_006094)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC208491
Predicted MW	13 kDa
Protein Sequence	Sequence Link (showhide) >RC208491 protein sequence Red=Cloning site Green=Tags(s) MPACRLGPLAAALLLSLLLFGFTLVSGTGAEKTGVCPELQADQNCTQECVSDSECADNLKCCSAGCATFC SLPNDKEGSCPQVNINFPQLGLCRDQCQVDSQCPGQMKCCRNGCGKVSCVTPNF TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_006094
RefSeq Size	570
RefSeq ORF	372
Synonyms	dJ461P17.6; EDDM4; HE4; WAP5
Locus ID	10406
Cytogenetics	20q13.12
Summary	This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008]
Protein Families	Secreted Protein, Transmembrane

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