RDH10 (NM_172037) Human Mass Spec Standard

Specifications

Product Data
Description	RDH10 MS Standard C13 and N15-labeled recombinant protein (NP_742034)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC208980
Predicted MW	38.1 kDa
Protein Sequence	Sequence Link (showhide) >RC208980 protein sequence Red=Cloning site Green=Tags(s) MNIVVEFFVVTFKVLWAFVLAAARWLVRPKEKSVAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINT QSNEETAGMVRHIYRDLEAADAAALQAGNGEEEILPHCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVS VLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDY CASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFRGCRIRKEIEPFLPPLKPDYCVKQAMKAI LTDQPMICTPRLMYIVTFMKSILPFEAVVCMYRFLGADKCMYPFIAQRKQATNNNEAKNGI TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_742034
RefSeq Size	3981
RefSeq ORF	1023
Synonyms	SDR16C4
Locus ID	157506
Cytogenetics	8q21.11
Summary	This gene encodes a retinol dehydrogenase, which converts all-trans-retinol to all-trans-retinal, with preference for NADP as a cofactor. Studies in mice suggest that this protein is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development. [provided by RefSeq, Dec 2011]
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Metabolic pathways, Retinol metabolism

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