GM CSF (CSF2) (NM_000758) Human Mass Spec Standard
CAT＃: PH311109
CSF2 MS Standard C13 and N15-labeled recombinant protein (NP_000749)
View other "GM CSF" proteins (7)
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CNY 19520.00
Product images
CNY 3080.00
CNY 1999.00
CNY 2700.00
Specifications
| Product Data | |
| Description | CSF2 MS Standard C13 and N15-labeled recombinant protein (NP_000749) |
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC211109 |
| Predicted MW | 16.3 kDa |
| Protein Sequence |
>RC211109 protein sequence
Red=Cloning site Green=Tags(s) MWLQSLLLLGTVACSISAPARSPSPSTQPWEHVNAIQEARRLLNLSRDTAAEMNETVEVISEMFDLQEPT CLQTRLELYKQGLRGSLTKLKGPLTMMASHYKQHCPPTPETSCATQIITFESFKENLKDFLLVIPFDCWE PVQE TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Reference Data | |
| RefSeq | NP_000749 |
| RefSeq Size | 800 |
| RefSeq ORF | 432 |
| Synonyms | CSF; GMCSF |
| Locus ID | 1437 |
| Cytogenetics | 5q31.1 |
| Summary | The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. This gene plays a role in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been detected in SARS-CoV-2 infected patients that develop acute respiratory distress syndrome. Mice deficient in this gene or its receptor develop pulmonary alveolar proteinosis. [provided by RefSeq, Aug 2020] |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein |
| Protein Pathways | Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC400257 | CSF2 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
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| LY400257 | Transient overexpression lysate of colony stimulating factor 2 (granulocyte-macrophage) (CSF2) |
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| TP311109 | Recombinant protein of human colony stimulating factor 2 (granulocyte-macrophage) (CSF2), 20 µg |
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| TP720003 | Recombinant protein of human colony stimulating factor 2 (granulocyte-macrophage) (CSF2) |
CNY 1800.00 |
|
| TP720031 | Recombinant protein of human colony stimulating factor 2 (granulocyte-macrophage) (CSF2) |
CNY 1800.00 |
|
| TP721106 | Purified recombinant protein of Human colony stimulating factor 2 (granulocyte-macrophage) (CSF2) |
CNY 1800.00 |
|
| TP723720 | Purified recombinant protein of Human colony stimulating factor 2 (granulocyte-macrophage) (CSF2) |
CNY 4090.00 |
