GM CSF (CSF2) (NM_000758) Human Recombinant Protein
CAT＃: TP723720
Purified recombinant protein of Human colony stimulating factor 2 (granulocyte-macrophage) (CSF2)
View other "GM CSF" proteins (7)
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CNY 4090.00
Product images
CNY 1999.00
CNY 2700.00
Specifications
| Product Data | |
| Species | Human |
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence |
Human GM-CSF, the region of Ala18- Glu144, from gene Accession# NM_000758
|
| Tag | Tag Free |
| Predicted MW | 14.5 kDa |
| Concentration | lot specific |
| Purity | >98%, as determined by Coomassie stained SDS-PAGE. |
| Buffer | 1 x PBS |
| Storage | Store at -80°C. |
| Stability | Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles. |
| Bioactivity | The ED50 is 0.10- 0.30 ng/ml, corresponding to a specific activity of 1 - 0.33 X10^7 units/mg, determined by a dose dependent TF-1 cell proliferation. |
| Endotoxin | Less than 0.01 ng per µg protein as determined by the LAL method |
| Reference Data | |
| RefSeq | NP_000749 |
| Locus ID | 1437 |
| UniProt ID | P04141 |
| Refseq Size | 800 |
| Cytogenetics | 5q31.1 |
| Refseq ORF | 432 |
| Synonyms | CSF; GMCSF |
| Summary | The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. This gene plays a role in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been detected in SARS-CoV-2 infected patients that develop acute respiratory distress syndrome. Mice deficient in this gene or its receptor develop pulmonary alveolar proteinosis. [provided by RefSeq, Aug 2020] |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein |
| Protein Pathways | Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway |
Documents
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Resources
| 蛋白相关资源 |
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC400257 | CSF2 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY400257 | Transient overexpression lysate of colony stimulating factor 2 (granulocyte-macrophage) (CSF2) |
CNY 3080.00 |
|
| PH311109 | CSF2 MS Standard C13 and N15-labeled recombinant protein (NP_000749) |
CNY 19520.00 |
|
| TP311109 | Recombinant protein of human colony stimulating factor 2 (granulocyte-macrophage) (CSF2), 20 µg |
CNY 2900.00 |
|
| TP720003 | Recombinant protein of human colony stimulating factor 2 (granulocyte-macrophage) (CSF2) |
CNY 1800.00 |
|
| TP720031 | Recombinant protein of human colony stimulating factor 2 (granulocyte-macrophage) (CSF2) |
CNY 1800.00 |
|
| TP721106 | Purified recombinant protein of Human colony stimulating factor 2 (granulocyte-macrophage) (CSF2) |
CNY 1800.00 |
