Protor 1 (PRR5) (NM_015366) Human Mass Spec Standard

CAT#: PH317823

PRR5 MS Standard C13 and N15-labeled recombinant protein (NP_056181)



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CNY 19520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description PRR5 MS Standard C13 and N15-labeled recombinant protein (NP_056181)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC217823
Predicted MW 41.4 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_056181
RefSeq Size 1653
RefSeq ORF 1137
Synonyms FLJ20185k; PP610; PROTOR-1; PROTOR1
Locus ID 55615
Cytogenetics 22q13.31
Summary This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene. [provided by RefSeq, Nov 2010]
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