PCSK9 (NM_174936) Human Mass Spec Standard
CAT＃: PH320000
PCSK9 MS Standard C13 and N15-labeled recombinant protein (NP_777596)
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CNY 19520.00
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CNY 4840.00
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Specifications
| Product Data | |
| Description | PCSK9 MS Standard C13 and N15-labeled recombinant protein (NP_777596) |
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC220000 |
| Predicted MW | 71 kDa |
| Protein Sequence |
RC220000
|
| Tag | C-Myc/DDK |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Reference Data | |
| RefSeq | NP_777596 |
| RefSeq Size | 3636 |
| RefSeq ORF | 2076 |
| Synonyms | FH3; FHCL3; HCHOLA3; LDLCQ1; NARC-1; NARC1; PC9 |
| Locus ID | 255738 |
| Cytogenetics | 1p32.3 |
| Summary | This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] |
| Protein Families | Secreted Protein |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC403563 | PCSK9 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1470.00 |
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| LY403563 | Transient overexpression lysate of proprotein convertase subtilisin/kexin type 9 (PCSK9) |
CNY 4840.00 |
|
| TP320000 | Recombinant protein of human proprotein convertase subtilisin/kexin type 9 (PCSK9), 20 µg |
CNY 2900.00 |
|
| TP700053 | Recombinant protein of secreted form of human proprotein convertase subtilisin/kexin type 9 (PCSK9) |
CNY 6650.00 |
|
| TP720768 | Purified recombinant protein of Human proprotein convertase subtilisin/kexin type 9 (PCSK9) |
CNY 1800.00 |
|
| TP721051 | Purified recombinant protein of Human proprotein convertase subtilisin/kexin type 9 (PCSK9), D374Y mutant. |
CNY 1800.00 |
|
| TP723879 | Purified recombinant protein of Human proprotein convertase subtilisin/kexin type 9 (PCSK9) |
CNY 5240.00 |
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