PCSK9 (NM_174936) Human Recombinant Protein
CAT＃: TP723879
Purified recombinant protein of Human proprotein convertase subtilisin/kexin type 9 (PCSK9)
View other "PCSK9" proteins (7)
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CNY 5240.00
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CNY 1999.00
CNY 2700.00
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Specifications
| Product Data | |
| Species | Human |
| Expression Host | CHO |
| Expression cDNA Clone or AA Sequence |
Human PCSK9, the region of Arg29-Gln692, from gene Accession# NM_174936
|
| Tag | C-His |
| Predicted MW | 73 kDa |
| Concentration | lot specific |
| Purity | >90%, as determined by Coomassie stained SDS-PAGE. |
| Buffer | 25 mM sodium Acetate, 150 mM NaCl, pH 5.0 |
| Storage | Store at -80°C. |
| Stability | Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles. |
| Bioactivity | When recombinant human LDLR is immobilized at 1 µg/mL, recombinant human PCSK9 binds with EC50 of 0.04 - 0.2 µg/mL in a functional ELISA. |
| Endotoxin | Less than 1 EU per µg protein as determine by the LAL method |
| Reference Data | |
| RefSeq | NP_777596 |
| Locus ID | 255738 |
| UniProt ID | Q8NBP7 |
| Refseq Size | 3636 |
| Cytogenetics | 1p32.3 |
| Refseq ORF | 2076 |
| Synonyms | FH3; FHCL3; HCHOLA3; LDLCQ1; NARC-1; NARC1; PC9 |
| Summary | This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] |
| Protein Families | Secreted Protein |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC403563 | PCSK9 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1470.00 |
|
| LY403563 | Transient overexpression lysate of proprotein convertase subtilisin/kexin type 9 (PCSK9) |
CNY 4840.00 |
|
| PH320000 | PCSK9 MS Standard C13 and N15-labeled recombinant protein (NP_777596) |
CNY 19520.00 |
|
| TP320000 | Recombinant protein of human proprotein convertase subtilisin/kexin type 9 (PCSK9), 20 µg |
CNY 2900.00 |
|
| TP700053 | Recombinant protein of secreted form of human proprotein convertase subtilisin/kexin type 9 (PCSK9) |
CNY 6650.00 |
|
| TP720768 | Purified recombinant protein of Human proprotein convertase subtilisin/kexin type 9 (PCSK9) |
CNY 1800.00 |
|
| TP721051 | Purified recombinant protein of Human proprotein convertase subtilisin/kexin type 9 (PCSK9), D374Y mutant. |
CNY 1800.00 |
Clone OTI2B5, Anti-His mouse monoclonal antibody
PCSK9 mouse monoclonal antibody,clone OTI4G9
